中文字幕网伦射乱中文-超清中文乱码字幕在线观看-亚洲v国产v欧美v久久久久久-久久性网-手机在线成人av-成人六区-国产人与zoxxxx另类一一-青青草国产久久精品-蜜桃av久久久一区二区三区麻豆-成人av一区二区免费播放-在线视频麻豆-www爱爱-成人免费看片视频-性欧美老肥妇喷水-五月99久久婷婷国产综合亚洲-亚洲最色-各种含道具高h调教1v1男男-91丨porny丨国产-国产精品无码专区在线观看不卡-大香伊人

British AI robot finds malaria killer in common toothpaste ingredient

Source: Xinhua| 2018-01-19 16:40:58|Editor: pengying
Video PlayerClose

SAN FRANCISCO, Jan. 18 (Xinhua) -- An artificial intelligence (AI) robot made by a British university has become a big hero after it helped scientists find a malaria killer in a common toothpaste ingredient, a new study revealed Thursday.

Scientists at the university of Cambridge in Britain used the "Robot Scientist," Eve, in a high-throughput screen and discovered that triclosan, an ingredient found in many toothpastes, may help fight against strains of a malaria parasite that have grown resistant to one of the currently-used drugs to treat the disease.

The findings of the study by the Cambridge researchers were published in the journal Scientific Reports on Thursday.

With the help of the AI-powered Eve, the researchers discovered that triclosan inhibits the spread of a kind of enzyme of the malaria parasite, called DHFR, thus stopping the growth of the parasite in the blood.

The discovery challenged a previous assumption that triclosan inhibits the growth in culture of the malaria parasite Plasmodium during the blood-stage, because it is targeting an enzyme known as enoyl reductase (ENR) found in the liver.

The Cambridge scientists discovered that triclosan was able to target and act on the DHFR enzyme even in parasites that were resistant to the antimalarial drug, pyrimethamine.

Malaria is spread to humans by the bites of a mosquito infected with malaria parasites that are transferred into their bloodstream via its saliva.

The parasites mature and reproduce in the liver of humans, which eventually hijack red blood cells and spread around the body, causing symptoms and even life-threatening complications.

With the new function of triclosan, which inhibits both ENR and DHFR, the researchers believe it is possible that the parasite may be targeted at both the liver stage and the later blood stage.

"The discovery by our robot 'colleague' Eve that triclosan is effective against malaria targets offers hope that we may be able to use it to develop a new drug," said Elizabeth Bilsland, lead author of the study.

Robot Eve was developed by a group of scientists at the British universities of Manchester, Aberystwyth in Wales, and Cambridge.

The development was led by Professor Ross King from the Manchester Institute of Biotechnology at the University of Manchester.

It automates and speeds up the drug discovery process, including auto testing of hypotheses to explain observations, running experiments, and automating high-throughput hypothesis-led research.

AI and machine learning make it possible to create automated scientists that "take an intelligent approach to science," which could greatly speed up the drug discovery progress, King said.

TOP STORIES
EDITOR’S CHOICE
MOST VIEWED
EXPLORE XINHUANET
010020070750000000000000011100001369085921